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Molfinity

KSI-6666 - CAS 1807873-14-8

KSI-6666 - CAS 1807873-14-8

MF-0121820-01

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Product Details

  • Bioactivity

    KSI-6666 is an orally effective competitive antagonist of sphingosine 1-phosphate receptor 1 (S1PR1), with an IC50 value of 6.4 nM. It exhibits anti-inflammatory activity in models of autoimmune encephalomyelitis and T-cell transfer-induced colitis.

  • Target

    LPL Receptor

  • Related Pathways

    GPCR/G Protein

  • CAS Number

    1807873-14-8

  • Molecular Formula

    C23H26ClF3N2O2

  • Molecular Weight

    454.91

  • SMILES

    O=C(O)C1CN(CC2=CC(=CC=C2C)C(N(C3=CC=C(Cl)C(=C3)C(F)(F)F)CC)C)C1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound