KT-474 - CAS 2432994-31-3

KT-474 (KYM-001) is a PROTAC degrader targeting interleukin-1 receptor-associated kinase 4 (IRAK4) with antitumor activity for the study of autoimmune, inflammatory, and cardiovascular disease disorders.

PROTACs, Apoptosis, IRAK

Apoptosis, NF-κB, Immunology/Inflammation, PROTAC

2432960

0.9957

C44H49F2N11O6

865.93

O=C1N(C=2C(=C(C#CCOC3CCN(C[C@H]4CC[C@@H](CC4)N5C=C(NC(=O)C6=C7N(N=C6)C=CC(=N7)N8[C@@]9(C[C@](C8)(OC9)[H])[H])C(C(F)F)=N5)CC3)C=CC2)N1C)C%10C(=O)NC(=O)CC%10

-20°C

Ice Packs

PROTAC