KT5823 - CAS 126643-37-6

KT5823 is a selective and potent cGMP-dependent protein kinase (PKG) inhibitor with inhibitory effects on PKA and PKC.KT5823 increases thyroid-stimulating hormone-induced (Na+/I- symporter) NIS expression and iodide ion uptake by modulating sodium iodide symporter protein expression and activity in thyroid cells. KT5823 induces apoptosis.

Antibiotic, Antibacterial, Apoptosis, PKA, PKC

Tyrosine Kinase/Adaptors, Apoptosis, Chromatin/Epigenetic, Microbiology/Virology, Cytoskeletal Signaling

126600

0.95

C29H25N3O5

495.53

C[C@]12N3C=4C5=C(C6=C(C4C=7C3=CC=CC7)CN(C)C6=O)C=8C(N5[C@](O1)(C[C@@]2(C(OC)=O)OC)[H])=CC=CC8

-20°C

Ice Packs

Small Compound