KTX-955 - CAS 2573302-50-6

KTX-955, a potent IRAK4 degrader, exhibits DC50 values of 5 nM for IRAK4 and 130 nM for Ikaros. It is primarily utilized in anticancer research [1] [2].

PROTACs, IRAK, Others

Immunology/Inflammation, Others, PROTAC, NF-κB

2573246

C46H51F3N8O7

884.94

CC(C)(O)c1cc2nn(cc2cc1NC(=O)c1cccc(n1)C(F)(F)F)[C@H]1CC[C@H](CN2CCC(CC2)O[C@H]2C[C@@H](C2)Nc2cccc3C(=O)N(C4CCC(=O)NC4=O)C(=O)c23)CC1

-20°C

Ice Packs

Small Compound