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Molfinity
KU-0060648 - CAS 881375-00-4
KU-0060648 - CAS 881375-00-4
SKU:MF-0096647-01
Regular price
$50.37 USD
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$50.37 USD
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Product Details
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Bioactivity
KU-0060648 is a dual inhibitor of DNA-PK and PI3Kα, PI3Kβ, PI3Kδ with IC50 values of 8.6 nM, 4 nM, 0.5 nM, and 0.1 nM respectively, and demonstrates less inhibition of PI3Kγ with an IC50 of 0.59 μM.
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Target
MTOR, DNA-PK, PI3K
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Related Pathways
PI3K/Akt/mTOR signaling, DNA Damage/DNA Repair
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CAS Number
881375-00-4
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Purity
0.9921
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Molecular Formula
C33H34N4O4S
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Molecular Weight
582.71
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SMILES
CCN1CCN(CC(=O)Nc2ccc(-c3cccc4c3oc(cc4=O)N3CCOCC3)c3sc4ccccc4c23)CC1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound