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Molfinity

KWR095 - CAS 3057980-16-9

KWR095 - CAS 3057980-16-9

MF-0113958-01

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Product Details

  • Bioactivity

    KWR095 is an orally active inhibitor of WRN, demonstrating an IC50 of 0.032 μM against WRN ATPase. It disrupts the double-stranded helicase activity of WRN and inhibits tumor cell proliferation, exhibiting antitumor properties.

  • Target

    DNA/RNA Synthesis

  • Related Pathways

    DNA Damage/DNA Repair, Cell Cycle/Checkpoint

  • CAS Number

    3057955

  • Molecular Formula

    C33H31ClF3N9O4

  • Molecular Weight

    710.105

  • SMILES

    O=C(C1=NC=CC=2C=CNC21)N3CCN(C=4C(=O)N5N=C(N=C5N(C4CC)CC(=O)NC6=CC=C(C=C6Cl)C(F)(F)F)C7=CCOCC7)CC3

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound