KY386 - CAS 2787598-01-8

KY386 is a potent and selective DHX33 helicase inhibitor with an IC50 value of 19 nM. It demonstrates significant anti-cancer activity in DHX33-overexpressing U251-MG cell strain, achieving an IC50 of 20 nM, and exhibits moderate metabolic stability [1].

Others, DNA/RNA Synthesis

DNA Damage/DNA Repair, Others, Cell Cycle/Checkpoint

2787598-01-8

C21H19N5O2S

405.47

N#CC=1C=C(SC1N2C(=CC(C(=O)NC3=NC=4C=CC(OC)=CC4N3)=C2C)C)C

-20°C

Ice Packs

Small Compound