L-368899 free base - CAS 148927-60-0

L-368899 is a non-peptide and orally active antagonist of oxytocin receptor (IC50: 8.9 nM) . It displays 40-fold selectivity over vasopressin V1a and V2 receptors (IC50: 370 and 570 nM respectively) .

Oxytocin Receptor, Others

Others, Endocrinology/Hormones, GPCR/G Protein

148867

C26H42N4O5S2

554.77

[H][C@@]12CC[C@@](CS(=O)(=O)N3CCN(CC3)c3ccccc3C)([C@H](C1)NC(=O)[C@@H](N)CCS(C)(=O)=O)C2(C)C |@:35,TLB:24:22:35:2.3|

-20°C

Ice Packs

Small Compound