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Molfinity

L-745870 hydrochloride - CAS 1173023-36-3

L-745870 hydrochloride - CAS 1173023-36-3

SKU:MF-0015459-01

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  • Bioactivity

    L-745870 hydrochloride has excellent brain penetration. L-745870 hydrochloride is a high-affinity, selective and orally active human dopamine D4 receptor antagonist with a Ki of 0.43 nM, and considerably weaker D2 receptor affinity with a Ki of 960 nM and D3 receptor affinity with a Ki of 2300 nM.

  • Target

    Dopamine Receptor

  • Related Pathways

    GPCR/G Protein, Neuroscience

  • CAS Number

    1172984

  • Purity

    0.9958

  • Molecular Formula

    C18H20Cl2N4

  • Molecular Weight

    363.28

  • SMILES

    Cl.Clc1ccc(cc1)N1CCN(Cc2c[nH]c3ncccc23)CC1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound