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L-745870 hydrochloride - CAS 1173023-36-3
L-745870 hydrochloride - CAS 1173023-36-3
SKU:MF-0015459-01
Regular price
$31.68 USD
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$31.68 USD
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Product Details
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Bioactivity
L-745870 hydrochloride has excellent brain penetration. L-745870 hydrochloride is a high-affinity, selective and orally active human dopamine D4 receptor antagonist with a Ki of 0.43 nM, and considerably weaker D2 receptor affinity with a Ki of 960 nM and D3 receptor affinity with a Ki of 2300 nM.
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Target
Dopamine Receptor
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Related Pathways
GPCR/G Protein, Neuroscience
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CAS Number
1172984
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Purity
0.9958
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Molecular Formula
C18H20Cl2N4
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Molecular Weight
363.28
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SMILES
Cl.Clc1ccc(cc1)N1CCN(Cc2c[nH]c3ncccc23)CC1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound