1 1

Molfinity

L-778123 Dihydrochloride - CAS 183499-56-1

L-778123 Dihydrochloride - CAS 183499-56-1

MF-0144587-01

$1,383.80 USD
$1,383.80 USD
Sale Sold out
Taxes included.
Size
View full details

Product Details

  • Bioactivity

    L-778123 is an inhibitor of FPTase and GGPTase-I, which was developed in part because it can completely inhibit Ki-Ras prenylation. The combination of L-778,123 and radiotherapy at dose level 1 showed acceptable toxicity in patients with locally advanced pancreatic cancer. Radiosensitization of a patient-derived pancreatic cancer cell line was observed.

  • Target

    Others, Transferase

  • Related Pathways

    Others, Metabolism

  • CAS Number

    183442

  • Molecular Formula

    C22H22Cl3N5O

  • Molecular Weight

    478.802

  • SMILES

    Cl.Cl.Clc1cccc(c1)N1CCN(Cc2cncn2Cc2ccc(cc2)C#N)CC1=O

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound