L-803087 TFA - CAS 1786412-46-1

L-803087 TFA is a highly potent and selective agonist of the somatostatin sst4 receptor, exhibiting a Ki value of 0.7 nM. It displays a remarkable selectivity, being over 280-fold more preferential for the sst4 receptor compared to other somatostatin receptors. Furthermore, L-803087 TFA promotes AMPA-mediated synaptic responses in hippocampal preparations and enhances kainate-induced seizures in mice.

Others, Somatostatin

Others, GPCR/G Protein

1786365

C27H30F5N5O5

599.55

OC(=O)C(F)(F)F.COC(=O)[C@H](CCCNC(N)=N)NC(=O)CCCc1c([nH]c2c(F)cc(F)cc12)-c1ccccc1

-20°C

Ice Packs

Small Compound