L-873724 - CAS 603139-12-4

L-873724 inhibits bone resorption. L-873724 is an effective, selective, and reversible non-basic cathepsin K inhibitor (IC50s: 0.2, 178, 264, and 5239 nM for cathepsin K, cathepsin S, cathepsin L, cathepsin B, respectively) . L-873724 also shows an IC50 of 0.5 nM for rabbit cathepsin K.

Others, Cysteine Protease

Others, Proteases/Proteasome

603123

C23H26F3N3O3S

481.53

CC(C)C[C@H](N[C@@H](c1ccc(cc1)-c1ccc(cc1)S(C)(=O)=O)C(F)(F)F)C(=O)NCC#N

-20°C

Ice Packs

Small Compound