L-Alloisoleucine - CAS 1509-34-8

L-Alloisoleucine (L-allo-Isoleucine) is a branched chain amino acid and is a stereoisomer of L-isoleucine. It is a common constituent of human plasma (albeit at low levels) . L-alloisoleucine is produced as a byproduct of isoleucine transamination. Plasma L-alloisoleucine, which is derived from L-isoleucine in vivo, can be used for the diagnosis of maple syrup urine disease (MSUD), a genetic disorder. Indeed, plasma L-alloisoleucine levels above 5 μmol/L is the most specific and most sensitive diagnostic marker for all forms of MSUD.

Endogenous Metabolite

Metabolism

1467

0.9996

C6H13NO2

131.17

CC[C@@H](C)[C@H](N)C(O)=O

-20°C

Ice Packs

Natural Product