L-I-OddU - CAS 207920-87-4

L-I-OddU, a potent and selective anti-Epstein-Barr virus (EBV) agent, is a L-5'-halo-dioxolane nucleoside analogue. It demonstrates antiviral activity by effectively suppressing replicative EBV DNA and viral protein synthesis [1] [2]. With an EC 50 value of 0.03 μM, L-I-OddU exhibits high potency against EBV while maintaining low cytotoxicity, as indicated by its CC 50 value of 1000 nM.

Nucleoside Antimetabolite/Analog, Antifection, DNA/RNA Synthesis, Others

Cell Cycle/Checkpoint, Microbiology/Virology, Others, DNA Damage/DNA Repair

207829

C8H9IN2O5

340.07

O=C1N([C@H]2O[C@@H](CO)OC2)C=C(I)C(=O)N1

-20°C

Ice Packs

Small Compound