L-Kynurenine-d4-1 - CAS 194546-33-3

L-Kynurenine-d4-1 is a deuterated compound of L-Kynurenine. L-Kynurenine has a CAS number of 2922-83-0. L-Kynurenine is a key intermediate in the breakdown pathway of tryptophan. L-Kynurenine is a substrate of kynureninase, KMO, and KAT associated with the suppression of antitumor immune responses. It has been shown to inhibit allogeneic T-cell proliferation and to increase malignant U87 glioma cell invasion into a collagen matrix.

Aryl Hydrocarbon Receptor, Endogenous Metabolite

Metabolism, Immunology/Inflammation

194546-33-3

C10H8D4N2O3

212.24

C1([2H])C([2H])=C(N)C(C(=O)C[C@H](N)C(=O)O)=C([2H])C=1[2H]

-20°C

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