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L-NIL dihydrochloride - CAS 159190-45-1
L-NIL dihydrochloride - CAS 159190-45-1
SKU:MF-0109223-01
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$140.38 USD
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$140.38 USD
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Product Details
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Bioactivity
L-NIL HCl is a relatively selective iNOS inhibitor (IC50s: 0.4-3.3, 8-38, and 17-92 μM for iNOS, eNOS, and nNOS) . L-NIL effectively inhibits iNOS both in vitro and in vivo. L-NIL has been used to demonstrate a critical role for iNOS in the immune response to infection by the protozoan L. major.
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Target
NO Synthase, Others
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Related Pathways
Others, Immunology/Inflammation
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CAS Number
159144
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Molecular Formula
C8H19Cl2N3O2
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Molecular Weight
260.16
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SMILES
Cl.Cl.CC(N)=NCCCCC(N)C(O)=O
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound