L-R4W2 - CAS 206350-79-0

Vanilloid TRPV1 (VR1) receptor antagonist peptide (IC50 ~ 0.1 μM) ; blocks Ca2+ currents in dorsal root ganglion neurons. Analgesic in vivo.

TRP/TRPV Channel

Membrane transporter/Ion channel

206271

C46H71N21O6

1014.2

C([C@@H](C(N[C@@H](CC=1C=2C(NC1)=CC=CC2)C(N)=O)=O)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CCCNC(=N)N)N)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)C=3C=4C(NC3)=CC=CC4

-20°C

Ice Packs

Peptide