L-Sepiapterin - CAS 17094-01-8

L-Sepiapterin, also known as Sepiapterin, is a precursor compound crucial for the production of tetrahydrobiopterin (BH4), which serves as a coenzyme for endothelial nitric oxide synthase (eNOS) . This compound demonstrates its efficacy by improving endothelial dysfunction in small mesenteric arteries from db/db mice and promoting angiogenesis. Moreover, L-Sepiapterin exerts inhibitory effects on cellular proliferation and migration in ovarian cancer cells through the down-regulation of p70S6K-dependent vascular endothelial growth factor receptor-2 (VEGFR-2) expression[1][2].

Others, Endogenous Metabolite

Metabolism, Others

17094-01-8

C9H11N5O3

237.22

O=C1C2=C(NCC(C([C@H](C)O)=O)=N2)NC(N)=N1

-20°C

Ice Packs

Natural Product