L-Thyroxine-13C6 - CAS 720710-30-5

L-Thyroxine-13C6 is the 13C labeled compound of L-Thyroxine. L-Thyroxine has a CAS number of 51-48-9. Levothyroxine is the major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.

Endogenous Metabolite, Thyroid hormone receptor (THR)

Metabolism, Endocrinology/Hormones

720710-30-5

13C4C11H11I4NO4

782.83

O(C1=CC(I)=C(O)C(I)=C1)[13C]2=[13C](I)[13CH]=[13C](C[C@@H](C(O)=O)N)[13CH]=[13C]2I

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