Laccaridione B - CAS 320369-81-1

Laccaridione B inhibits the activity of serine proteases. It exhibits inhibitory effects on trypsin, papain, thermolysin, collagenase, and zinc metalloprotease with IC50 values of 10.9 μg/mL, 5.1 μg/mL, 8.4 μg/mL, 5.7 μg/mL, and 3.0 μg/mL, respectively. Additionally, Laccaridione B shows significant antiproliferative activity against L-929, K-562, and HeLa cells, with IC50 values of 2.4 μg/mL, 1.8 μg/mL, and 13.9 μg/mL, respectively.

Serine Protease

Proteases/Proteasome

320369-81-1

C23H26O6

398.449

O(CC)C1C2=C(C=C3C(=C2O)C(=O)C(=O)C(OC)=C3)C=C(\C(=C\C(CC)C)\C)O1

-20°C

Ice Packs

Natural Product