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Ladiratuzumab vedotin - CAS 1629760-29-7
Ladiratuzumab vedotin - CAS 1629760-29-7
SKU:MF-0100612-01
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Product Details
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Bioactivity
Ladiratuzumab vedotin (SGN-LIV1A) is an ADC (IC 50: 5.6 nM for LIV-1) that targets LIV-1. This compound is composed of a humanized IgG1 monoclonal antibody, linked to MMAE via a protease-cleavable linker. It induces immunogenic cell death (ICD), which triggers an immune response. Ladiratuzumab vedotin is utilized in breast cancer research [1] [2] [3] [4].
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Target
Antibody-Drug Conjugates (ADCs)
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Related Pathways
Antibody-drug Conjugate/ADC Related
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CAS Number
1629760-29-7
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Inhibitory Antibodies