Laflunimus - CAS 147076-36-6

Laflunimus (HR325) is a DHODH inhibitor that inhibits immunoglobulin IgM and IgG secretion in vitro and in vivo, with an IC50=2.5 μm, and exerts an immunosuppressive effect by interfering with pyrimidine metabolism, and is used in the study of neuralgia.

Dehydrogenase, Prostaglandin Receptor, DNA/RNA Synthesis

Immunology/Inflammation, Metabolism, GPCR/G Protein, Cell Cycle/Checkpoint, DNA Damage/DNA Repair

147034

0.9986

C15H13F3N2O2

310.27

N(C(/C(=C(\O)/C1CC1)/C#N)=O)C2=CC(C)=C(C(F)(F)F)C=C2

-20°C

Ice Packs

Small Compound