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Lanraplenib - CAS 1800046-95-0

Lanraplenib - CAS 1800046-95-0

SKU:MF-0019877-01

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  • Bioactivity

    Lanraplenib (GS-9876) is a highly selective and orally active SYK inhibitor (IC50=9.5 nM) being developed for treating inflammatory diseases. It inhibits SYK activity in platelets via the glycoprotein VI (GPVI) receptor without prolonging bleeding time (BT) in monkeys or humans.

  • Target

    Syk

  • Related Pathways

    Tyrosine Kinase/Adaptors, Angiogenesis

  • CAS Number

    1799951

  • Purity

    0.9942

  • Molecular Formula

    C23H25N9O

  • Molecular Weight

    443.5

  • SMILES

    Nc1cncc(n1)-c1cn2ccnc2c(Nc2ccc(cc2)N2CCN(CC2)C2COC2)n1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound