Lanraplenib monosuccinate - CAS 1800046-97-2

Lanraplenib monosuccinate inhibits SYK activity in platelets via the glycoprotein VI (GPVI) receptor without prolonging bleeding time (BT) in monkeys or humans. Lanraplenib monosuccinate is a highly selective and orally active SYK inhibitor (IC50=9.5 nM) in development for the treatment of inflammatory diseases.

Syk

Tyrosine Kinase/Adaptors, Angiogenesis

1799947

C27H31N9O5

561.59

O=C(O)CCC(=O)O.N1=CC(=NC(=C1)C=2N=C(NC3=CC=C(C=C3)N4CCN(CC4)C5COC5)C6=NC=CN6C2)N

-20°C

Ice Packs

Small Compound