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Lapatinib ditosylate monohydrate - CAS 388082-78-8

Lapatinib ditosylate monohydrate - CAS 388082-78-8

SKU:MF-0003111-01

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  • Bioactivity

    Lapatinib ditosylate (Lapatinib tosilate) monohydrate is a tyrosine kinase receptor inhibitor used in the therapy of advanced breast cancer and other solid tumors. Lapatinib ditosylate monohydrate therapy is associated with transient elevations in serum aminotransferase levels and rare instances of clinically apparent acute liver injury.

  • Target

    Ferroptosis, Autophagy, EGFR

  • Related Pathways

    JAK/STAT signaling, Tyrosine Kinase/Adaptors, Autophagy, Apoptosis, Angiogenesis

  • CAS Number

    387996

  • Purity

    >99.99%

  • Molecular Formula

    C29H26ClFN4O4S·2 (C7H8O3S) ·H2O

  • Molecular Weight

    943.47

  • SMILES

    n1cnc(c2cc(ccc12)c1oc(cc1)CNCCS(=O)(=O)C)Nc1cc(c(cc1)OCc1cc(ccc1)F)Cl.c1(ccc(cc1)C)S(=O)(=O)O.O.c1(ccc(cc1)C)S(=O)(=O)O

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound