Laquinimod sodium - CAS 248282-07-7

Laquinimod (ABR-215062) sodium is a carboxamide derivative administered orally that serves as a powerful immunomodulator, designed to prevent inflammation and neurodegeneration within the central nervous system. This compound effectively diminishes the activation of astrocytic NF-κB, offering protection against Cuprizone-induced demyelination. It shows promise for the treatment of both relapsing-remitting (RR) and chronic progressive (CP) forms of multiple sclerosis (MS; RRMS or CPMS), in addition to its potential applications in the study of neurodegenerative diseases [1] [2] [3] [4].

Others, NF-κB, Apoptosis

Others, Apoptosis, NF-κB

248282-07-7

C19H16ClN2NaO3

378.79

[Na+].CCN(C(=O)c1c([O-])c2c(Cl)cccc2n(C)c1=O)c1ccccc1

-20°C

Ice Packs

Small Compound