Larotinib - CAS 1438072-11-7

Larotinib is an orally active, potent, and broad-spectrum tyrosine kinase inhibitor (TKI) with an IC50 of 0.6 nM for EGFR.

BTK, EGFR, IRAK, Tyrosine Kinases

Tyrosine Kinase/Adaptors, NF-κB, Angiogenesis, Immunology/Inflammation, JAK/STAT signaling

1438054

0.9973

C24H26ClFN4O4

488.94

N(C=1C2=C(C=C(OC)C(OCCCN3C[C@@]4([C@](C3)(OCCO4)[H])[H])=C2)N=CN1)C5=CC(Cl)=C(F)C=C5

-20°C

Ice Packs

Small Compound