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Larotrectinib - CAS 1223403-58-4

Larotrectinib - CAS 1223403-58-4

MF-0000416-01

$34.67 USD
$21.45 USD $34.67 USD
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Product Details

  • Bioactivity

    Larotrectinib (LOXO-101) is an orally administered inhibitor of the TRK kinase, demonstrating high selectivity exclusively for the TRK family of receptors (IC50s = 2-20 nM) .

  • Target

    Apoptosis, Trk receptor

  • Related Pathways

    Tyrosine Kinase/Adaptors, Apoptosis

  • CAS Number

    1223403-58-4

  • Purity

    >99.99%

  • Molecular Formula

    C21H22F2N6O2

  • Molecular Weight

    428.44

  • SMILES

    O[C@H]1CCN(C1)C(=O)Nc1cnn2ccc(nc12)N1CCC[C@@H]1c1cc(F)ccc1F

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound