LAS191859 - CAS 1420071-13-1

LAS191859 is a CRTH2/DP2 antagonist with IC50 values of 7.6, 9.58, 14 and 15.5nM for recombinant guinea pig, human, rat and mouse CRTH2/DP2 receptors, respectively. LAS191859 has a residence time half-life of 21h at CRTh2 that translates into a long-lasting in vivo efficacy that is independent of plasma levels

Others, Prostaglandin Receptor

Immunology/Inflammation, GPCR/G Protein, Others

1420057

C24H24F3N3O3

459.46

C(N(C(=O)C1CC1)CC)C2=C(N3C=4C(C(CC(O)=O)=C3)=CC=C(C)N4)C=CC(C(F)(F)F)=C2

-20°C

Ice Packs

Small Compound