LASSBio-2052 - CAS 2549160-15-6

LASSBio-2052, a derivative of N-acylhydrazone with antitumor activity against hepatocellular carcinoma (HCC), inhibits HCC cells HepG2 and Hep3B with IC50 values of 18 and 41 μM, respectively. LASSBio-2052 arrests the cell cycle at G2/M phase through downregulation of FOXM1 and induces apoptosis in HCC cells [1].

Others, Apoptosis, DNA/RNA Synthesis

Others, Cell Cycle/Checkpoint, DNA Damage/DNA Repair, Apoptosis

2549160-15-6

C23H20F3N3O3

443.42

C(NN=CC1=CC=C(C(F)(F)F)C=C1)(=O)C2=C(NCC3=CC(O)=C(OC)C=C3)C=CC=C2

-20°C

Ice Packs

Small Compound