Laulimalide - CAS 115268-43-4

Microtubule stabilizing agent. Potent inhibitor of cellular proliferation in cancer cell lines (IC50 reported to be 3-30 nM, dependent on cell line used) . Causes cells to arrest in the prometaphase of the cell cycle, prevents formation of bipolar spindle and increases kinetochore tension in preformed spindles.

Apoptosis, Microtubule Associated, Others

Others, Apoptosis, Cytoskeletal Signaling

115221

C30H42O7

514.65

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-20°C

Ice Packs

Small Compound