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Lazertinib - CAS 1903008-80-9
Lazertinib - CAS 1903008-80-9
SKU:MF-0016367-01
Regular price
$40.65 USD
Regular price
Sale price
$40.65 USD
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Product Details
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Bioactivity
Lazertinib (GNS-1480) is an effective, highly mutant-selective and irreversible EGFR-TKI with IC50 values of 1.7 nM, 2 nM, 5 nM, 20.6 nM and 76 nM for Del19/T790M, L858R/T790M, Del19, L85R and Wild type EGFR respectively.
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Target
EGFR
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Related Pathways
Angiogenesis, JAK/STAT signaling, Tyrosine Kinase/Adaptors
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CAS Number
1902919
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Purity
0.9996
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Molecular Formula
C30H34N8O3
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Molecular Weight
554.64
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SMILES
COc1cc(N2CCOCC2)c(NC(=O)C=C)cc1Nc1nccc(n1)-n1cc(CN(C)C)c(n1)-c1ccccc1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound