LBW242 - CAS 867324-12-7

LBW242 is a 3-mer and Smac mimetic and is an effective and orally active proapoptotic IAP inhibitor. LBW242 has activity against multiple myeloma and potentiates TRAIL- and anticancer drug-mediated cell death of ovarian cancer cells. LBW242 displays effects on mutant FLT3-expressing cells.

Others, FLT, IAP

Apoptosis, Angiogenesis, Tyrosine Kinase/Adaptors, Others

867305

C27H42N4O2

454.65

C([C@@H](NC([C@@H](NC)C)=O)[C@H]1CCCCC1)(=O)N2[C@]3([C@@](CC2)(CCN(CCC4=CC=CC=C4)C3)[H])[H]

-20°C

Ice Packs

Small Compound