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LC kinetic stabilizer-1 - CAS 2495750-19-9
LC kinetic stabilizer-1 - CAS 2495750-19-9
SKU:MF-0146101-01
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$1,647.05 USD
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$1,647.05 USD
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Product Details
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Bioactivity
LC kinetic stabilizer-1 is a potent, selective kinetic stabilizer for amyloidogenic immunoglobulin light chains, demonstrating EC50 values of 140 nM for WIL-FL* and 74.1 nM for WIL-FL*T46L/F49Y, respectively. Notably, WIL-FL represents an amyloidogenic FL LC dimer.
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Target
Others
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Related Pathways
Others
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CAS Number
2495722
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Molecular Formula
C27H31N5O3
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Molecular Weight
473.57
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SMILES
CC=1C=2C(=CC(N(CC)CC)=CC2)OC(=O)C1CCNC(NCC3=CC(=CC=C3)C4=CN=CN4)=O
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound