LC-MB12 - CAS 2828438-38-4

LC-MB12 is an orally active, selective and potent PROTAC FGFR2 complex that degrades FGFR2.LC-MB12 has antiproliferative and antitumor activity.LC-MB12 is used in the study of gastric cancer because of its inhibition of FGFR2 signaling.LC-MB12 has been shown to have antiproliferative and antitumor activity.LC-MB12 has been shown to have antiproliferative and antitumor activity.

FGFR, PROTACs

Tyrosine Kinase/Adaptors, PROTAC, Angiogenesis

2828438-38-4

0.9916

C43H44Cl2N10O8

899.78

O=C(NC=1C(Cl)=C(OC)C=C(OC)C1Cl)N(C=2N=CN=C(C2)NC3=CC=C(C=C3)N4CCN(C(=O)C5CCN(C6=CC=C7C(=O)N(C(=O)C7=C6)C8C(=O)NC(=O)CC8)CC5)CC4)C

-20°C

Ice Packs

PROTAC