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LC3-mHTT-IN-AN1 - CAS 486443-73-6

LC3-mHTT-IN-AN1 - CAS 486443-73-6

SKU:MF-0016683-01

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  • Bioactivity

    LC3-mHTT-IN-AN1 is a mHTT-LC3 linker compound that interacts with both mutant huntingtin protein (mHTT) and LC3B. LC3-mHTT-IN-AN1 targeted mHTT to autophagosomes reduces the levels of mHTT in an allele-selective manner in cultured Huntington disease (HD) mouse neurons.

  • Target

    ATTECs, Autophagy, ATG

  • Related Pathways

    PROTAC, Autophagy

  • CAS Number

    486364

  • Purity

    0.9726

  • Molecular Formula

    C15H9Br2NO3

  • Molecular Weight

    411.04

  • SMILES

    Oc1cc(\C=C2/C(=O)Nc3ccc(Br)cc23)cc(Br)c1O

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    PROTAC