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LC3-mHTT-IN-AN1 - CAS 486443-73-6
LC3-mHTT-IN-AN1 - CAS 486443-73-6
SKU:MF-0016683-01
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$36.16 USD
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$36.16 USD
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Product Details
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Bioactivity
LC3-mHTT-IN-AN1 is a mHTT-LC3 linker compound that interacts with both mutant huntingtin protein (mHTT) and LC3B. LC3-mHTT-IN-AN1 targeted mHTT to autophagosomes reduces the levels of mHTT in an allele-selective manner in cultured Huntington disease (HD) mouse neurons.
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Target
ATTECs, Autophagy, ATG
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Related Pathways
PROTAC, Autophagy
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CAS Number
486364
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Purity
0.9726
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Molecular Formula
C15H9Br2NO3
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Molecular Weight
411.04
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SMILES
Oc1cc(\C=C2/C(=O)Nc3ccc(Br)cc23)cc(Br)c1O
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
PROTAC