LCB 03-0110 dihydrochloride - CAS 1962928-28-4

LCB 03-0110 Dihydrochloride is a potent inhibitor of the c-Src kinase (IC50 = 1.3 nM) and tyrosine kinases in the BTK and SYK family, as well as in the DDR2 family. It inhibits LPS-induced activation of macrophages and TGF-β1-induced activation of fibroblasts in vitro, inhibits activation of macrophages and fibroblasts, and inhibits scarring in wound healing models.

Src

Angiogenesis, Tyrosine Kinase/Adaptors

1962896

0.999

C24H25Cl2N3O2S

490.45

Cl.Cl.Oc1cccc(Nc2ccnc3cc(sc23)-c2cccc(CN3CCOCC3)c2)c1

-20°C

Ice Packs

Small Compound