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LCL161 - CAS 1005342-46-0

LCL161 - CAS 1005342-46-0

MF-0000039-01

$57.09 USD
$40.95 USD $57.09 USD
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Product Details

  • Bioactivity

    LCL161 is a SMAC mimetic, an IAP antagonist with oral activity that inhibits XIAP (IC50=35 nM) in HEK293 cells and also inhibits cIAP1 (IC50=0.4 nM) in MDA-MB-231 cells. LCL161 has potential antitumor activity.

  • Target

    IAP

  • Related Pathways

    Apoptosis

  • CAS Number

    1005342-46-0

  • Purity

    0.9987

  • Molecular Formula

    C26H33FN4O3S

  • Molecular Weight

    500.63

  • SMILES

    C([C@@H](NC([C@@H](NC)C)=O)[C@H]1CCCCC1)(=O)N2[C@@H](CCC2)C3=NC(C(=O)C4=CC=C(F)C=C4)=CS3

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound