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Molfinity

LDHA-IN-8 - CAS 347380-13-6

LDHA-IN-8 - CAS 347380-13-6

SKU:MF-0097761-01

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  • Bioactivity

    LDHA-IN-8, a small molecule inhibitor of lactate dehydrogenase A (LDHA), inhibits the proliferation of pancreatic and lung cancer cells by inhibiting the activity of LDHA-catalyzed pyruvate in a dose-dependent manner (EC 50=14.54μM), decreasing the intracellular lactate content and increasing the intracellular reactive oxygen species (ROS) levels.

  • Target

    Dehydrogenase

  • Related Pathways

    Metabolism

  • CAS Number

    347361

  • Purity

    0.9973

  • Molecular Formula

    C15H14N4O2

  • Molecular Weight

    282.3

  • SMILES

    O=C1NC(=O)C(=CC=2C=C(N(C=3C=NC=CC3)C2C)C)N1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound