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LDHA-IN-8 - CAS 347380-13-6
LDHA-IN-8 - CAS 347380-13-6
SKU:MF-0097761-01
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$104.63 USD
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$104.63 USD
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Product Details
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Bioactivity
LDHA-IN-8, a small molecule inhibitor of lactate dehydrogenase A (LDHA), inhibits the proliferation of pancreatic and lung cancer cells by inhibiting the activity of LDHA-catalyzed pyruvate in a dose-dependent manner (EC 50=14.54μM), decreasing the intracellular lactate content and increasing the intracellular reactive oxygen species (ROS) levels.
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Target
Dehydrogenase
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Related Pathways
Metabolism
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CAS Number
347361
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Purity
0.9973
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Molecular Formula
C15H14N4O2
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Molecular Weight
282.3
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SMILES
O=C1NC(=O)C(=CC=2C=C(N(C=3C=NC=CC3)C2C)C)N1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound