LDHA-IN-9 - CAS 862719-04-8

LDHA-IN-9 (Compound 1g) is an LDH-A inhibitor with an IC50 of 25 nM. It inhibits the proliferation of DLD-1 cells by inducing apoptosis, with a GI50 of 27 μM. In mouse models, LDHA-IN-9 exhibits antitumor activity without significant toxicity at a dose of 25 mg/kg.

Apoptosis, Dehydrogenase

Metabolism, Apoptosis

862719-04-8

C17H22BrNO4

384.27

O=C(OC)C1=C(C=2C(Br)=CC=CC2N1O)COCCCCCC

-20°C

Ice Packs

Small Compound