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LDHA/PDKs-IN-1 - CAS 2490699-40-4

LDHA/PDKs-IN-1 - CAS 2490699-40-4

MF-0138501-01

$1,927.85 USD
$1,927.85 USD
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Product Details

  • Bioactivity

    LDHA/PDKs-IN-1 (compound 20e) is a highly effective dual inhibitor of PDKs and LDHA, with IC50 values of 0.8 μM and 0.15 μM, respectively. It significantly suppresses A549 cell proliferation (EC50 = 13.2 μM), reduces lactate formation, and enhances oxygen consumption, holding great promise for cancer research [1].

  • Target

    Others, PDK

  • Related Pathways

    PI3K/Akt/mTOR signaling, Others

  • CAS Number

    2490655

  • Molecular Formula

    C19H21FN2O4

  • Molecular Weight

    360.38

  • SMILES

    O(CCN1CCN(C(=O)C2=CC=C(F)C=C2)CC1)C=3C(=O)C=COC3C

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound