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LDHA/PDKs-IN-2 - CAS 2490699-44-8

LDHA/PDKs-IN-2 - CAS 2490699-44-8

MF-0141125-01

$1,927.85 USD
$1,927.85 USD
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Product Details

  • Bioactivity

    LDHA/PDKs-IN-2 (compound 20k) is a potent dual inhibitor of LDHA and PDKs, with IC50 values of 0.7 and 1.6 μM, respectively. It increases oxygen consumption, decreases lactate formation, and shows potential for cancer research by reducing the proliferation of A549 cells with an EC50 of 15.7 μM [1].

  • Target

    Others, PDK

  • Related Pathways

    Others, PI3K/Akt/mTOR signaling

  • CAS Number

    2490647

  • Molecular Formula

    C17H20N2O5

  • Molecular Weight

    332.35

  • SMILES

    C(=O)(N1CCN(CCOC=2C(=O)C=COC2C)CC1)C3=CC=CO3

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound