LDN-193189 Tetrahydrochloride - CAS 2310134-98-4

LDN-193189 Tetrahydrochloride (DM-3189 Tetrahydrochloride) is a selective inhibitor of BMP type I receptors, inhibiting ALK2 and ALK3 (IC50 = 5/30 nM), with weaker activity against ALK4, ALK5, and ALK7, and can be used for research into progressive osseous fibrodysplasia.

ALK, TGF-beta/Smad

Tyrosine Kinase/Adaptors, Angiogenesis, Stem Cells

2310032

0.9821

C25H26Cl4N6

552.33

C1(C2=C3N=CC(C4=CC=C(N5CCNCC5)C=C4)=CN3N=C2)=C6C=CC=CC6=NC=C1.Cl.Cl.Cl.Cl

-20°C

Ice Packs

Small Compound