Lecozotan HCl - CAS 433282-68-9

Lecozotan HCl (SRA-333) is a potent and selective 5-HT antagonist that significantly enhances KCl-stimulated glutamate and acetylcholine release from the hippocampal dentate gyrus and has cognitive enhancing properties. Chronic administration of Lecozotan HCl did not induce 5-HT (1A) receptor tolerance or desensitization in a behavioral model demonstrating 5-HT (1A) receptor function.

5-HT Receptor

Neuroscience, GPCR/G Protein

433205

0.9972

C28H30ClN5O3

520.02

[C@H](CN(C(=O)C1=CC=C(C#N)C=C1)C2=CC=CC=N2)(C)N3CCN(C4=C5C(=CC=C4)OCCO5)CC3.Cl

-20°C

Ice Packs

Small Compound