Leelamine hydrochloride - CAS 16496-99-4

Leelamine hydrochloride, a tricyclic diterpene extracted from pine tree bark, inhibits the transcriptional activity of the androgen receptor, known to regulate fatty acid synthesis [2,3]. This compound acts as a cannabinoid receptor type 1 (CB1) agonist and suppresses SREBP1-regulated fatty acid/lipid synthesis in prostate cancer cells, irrespective of androgen receptor status.

Cannabinoid Receptor, Androgen Receptor, Fatty Acid Synthase, Others

Metabolism, Others, Endocrinology/Hormones, GPCR/G Protein

16496-99-4

C20H32ClN

321.93

C[C@@]12C=3C(CC[C@]1([C@@](CN)(C)CCC2)[H])=CC(C(C)C)=CC3.Cl

-20°C

Ice Packs

Natural Product