Lenalidomide hemihydrate - CAS 847871-99-2

Lenalidomide hemihydrate is a derivative of Thalidomide, an orally active immunomodulator that acts as a molecular gel. It is a ligand for the ubiquitin E3 ligase cereblon, which selectively ubiquitinates and degrades two lymphoid transcription factors, IKZF1 and IKZF3, via the CRBN-CRL4 ubiquitin ligase.

IKZF, Molecular Glues, Apoptosis, Ligand for E3 Ligase, TNF

PROTAC, Immunology/Inflammation, Apoptosis

847770

>99.99%

C13H13N3O3.1/2H2O

268.28

O=C(C(N(CC1=C2C=CC=C1N)C2=O)CC3)NC3=O.O=C(C(N(CC4=C5C=CC=C4N)C5=O)CC6)NC6=O.[H]O[H]

-20°C

Ice Packs

PROTAC