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Lenalidomide-I - CAS 2207541-30-6
Lenalidomide-I - CAS 2207541-30-6
SKU:MF-0140639-01
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Product Details
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Bioactivity
Lenalidomide-I (Compound 72) is a derivative of the cereblon (CRBN) ligand, Lenalidomide, with affinity for E3 ubiquitin ligase. It facilitates the recruitment of CRBN protein. Lenalidomide-I can be utilized in PROTACs, such as the PROTAC BET degrader QCA570, by linking it to the targeted protein ligand through a linker.
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Target
Others, Ligand for E3 Ligase
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Related Pathways
PROTAC, Others
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CAS Number
2207505
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Molecular Formula
C13H11IN2O3
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Molecular Weight
370.14
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SMILES
O=C1N(CC=2C1=CC=CC2I)C3C(=O)NC(=O)CC3
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
PROTAC