Lenvatinib - CAS 417716-92-8

Lenvatinib (E7080) is a multi-target receptor tyrosine kinase inhibitor that inhibits VEGFR1-3, FGFR1-4, KIT, PDGFR, and RET, and has oral activity. Lenvatinib has the strongest inhibitory activity on VEGFR2 and VEGFR3 (IC50=4/5.2 nM) . Lenvatinib has strong anti-tumor activity.

C-RET, VEGFR, FGFR, PDGFR, c-Kit

Tyrosine Kinase/Adaptors, Apoptosis, Angiogenesis

417616

0.9996

C21H19ClN4O4

426.85

O(C=1C2=C(C=C(OC)C(C(N)=O)=C2)N=CC1)C3=CC(Cl)=C(NC(NC4CC4)=O)C=C3

-20°C

Ice Packs

Small Compound