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Molfinity

LEO 39652 - CAS 1445656-91-6

LEO 39652 - CAS 1445656-91-6

MF-0141951-01

$1,383.80 USD
$1,383.80 USD
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Product Details

  • Bioactivity

    LEO 39652, a dual-soft PDE4 inhibitor, demonstrates potent inhibition of PDE4 subtypes A, B, C, and D with respective IC50 values of 1.2 nM, 1.2 nM, 3.0 nM, and 3.8 nM. Additionally, it inhibits TNF-α with an IC50 of 6.0 nM, indicating its potential for topical Atopic dermatitis (AD) research [1].

  • Target

    Others, PDE

  • Related Pathways

    Metabolism, Others

  • CAS Number

    1445559

  • Molecular Formula

    C23H23N3O5

  • Molecular Weight

    421.45

  • SMILES

    COc1ccc(-c2ccc3C(=O)OCc3c2)n2nc(nc12)C1(CC1)C(=O)OCC(C)C

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound