Leptin (116-130) - CAS 189224-35-9

Leptin (116-130), a bioactive fragment of leptin, enhances synaptic plasticity in the hippocampus by promoting AMPA receptor trafficking to synapses. It preserves hippocampal synapse integrity and prevents neuronal cell death in amyloid toxicity models, showing promise for Alzheimer's disease (AD) research [1].

IGluR

Neuroscience, Membrane transporter/Ion channel

189180

C64H108N18O25S

1561.72

C([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC(=O)[C@H]1N(C([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CO)N)=O)CS)=O)CO)=O)CC(C)C)=O)CCC1)CCC(N)=O)=O)[C@@H](C)O)=O)CO)=O)=O)CC(C)C)=O)CCC(N)=O)=O)CCCCN)(=O)N2[C@H](C(N[C@H](C(N[C@H](C(O)=O)CO)=O)CCC(O)=O)=O)CCC2

-20°C

Ice Packs

Peptide